OIS at AAO 2015

Circadian Technologies (Opthea)

Nov 12, 2015 11:57am ‐ Nov 12, 2015 12:05pm


Circadian Technologies (ASX:CIR, Opthea) is developing OPT-302, a soluble form of VEGFR-3 that acts a VEGF-C/VEGF-D ‘trap’. Inhibition of VEGF-C/VEGF-D by OPT-302 inhibits angiogenesis and vessel leakage and targets resistance to VEGF-A inhibitors. OPT-302 is being investigated in a Phase 1/2A clinical trial in wet AMD patients in the US.


  • Megan Baldwin, PhD, CEO & Managing Director, Circadian Technologies (Opthea)

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